Metallothionein as a clonable high-density marker for cryo-electron microscopy
نویسندگان
چکیده
منابع مشابه
Introduction to high-resolution cryo-electron microscopy.
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The goal of cryo-electron microscopy (EM) is to reconstruct the 3-dimensional structure of a molecule from a collection of its 2-dimensional projected images. In this paper, we show that the basic premise of cryo-EM—patching together 2-dimensional projections to reconstruct a 3-dimensional object—is naturally one of Čech cohomology with SO(2)-coefficients. We deduce that every cryoEM reconstruc...
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ژورنال
عنوان ژورنال: Journal of Structural Biology
سال: 2012
ISSN: 1047-8477
DOI: 10.1016/j.jsb.2011.10.007